USC study identifies six new genes linked to pregnancy sickness - Newsy Today
Researchers at the University of Southern California have identified nine additional genes linked to hyperemesis gravidarum, the most severe form of pregnancy Researchers at the University of Southern California have identified nine additional genes linked to hyperemesis gravidarum, the most severe form of pregnancy sickness, which affects approximately 2% of pregnant women. The findings were published in Nature Genetics and led by the Keck School of Medicine of USC, the largest genetic study of the condition to date, analyzing data from 10,974 women with hyperemes gravidalum and 461,461 controls across European, Asian, African, and Latino ancestries. The strongest genetic link remains with GDF15, a gene that produces a hormone that spikes during pregnancy. Additional genes identified govern key pregnancy hormones, insulin, metabolism, and brain plasticity, suggesting that brain plastication may explain why patients develop strong, lasting aversions by associating specific foods with feeling sick. The study also revealed that TCF7L2 stands out as a major genetic risk factor for type 2 diabetes and gestational diabetes, potentially influencing glucagon-like peptide-1, a gut hormone that regulates blood sugar, appetite, and nausea. Current treatments such as Zofran only partially relieve symptoms for about half of patients.
Publicado : hace 2 días por Chief Editor en Health Science
Researchers at the University of Southern California have identified nine additional genes linked to hyperemesis gravidarum, the most severe form of pregnancy sickness, more than doubling the known ge... [3701 symbols]
Temas: Academia, USC
